Phenols are compounds with a specific chemical structure of an aromatic ring plus a hydroxyl group. They are found in fruits, vegetables, some grains and nuts, flavorings and spices. A salicylate is a type of phenolic compound. Phenols and polyphenols have antioxidant qualities and protective functions, which make some of them beneficial and desirable for most individuals.
An important chemical process that occurs in body tissues is called sulfation. Sulfation is the movement of sulfate (sulfur plus oxygen) ions from one body tissue to another. Sulfating molecules change the molecules’ character and behavior and how they act in the body. Connective tissue is sulfated for structural reasons and neuron tissue is sulfated to provide a protective sheath. Sulfation also causes molecules to vary in activity, solubility, and mobility. For the body to work properly, these sulfation processes must occur.
What is the relationship between phenolic compounds and sulfation? Phenols and salicylates use up a lot of sulfate in the body in order to be broken down. In other words, the phenols and salicylates compete for the body's sulfate stores. In certain individuals, breaking down phenolic compounds can provide a benefit by supporting the sulfation mechanism.
Phenol Assist™ contains a variety of enzymes to accomplish cell wall digestion, and other enzymes to assist in the total digestion of fruits, vegetables, grains, and spices. Below is a brief description of the enzymes present:
• Xylanase makes grains, fruits and vegetables that utilize xylose in their structure more digestible by breaking
some of the xylan bonds.
• CeraCalase™ is a proprietary blend of the National Enzyme Company that aids the breakdown of plant and
• Cellulase helps digest the cellulose fibers surrounding plant cells.
• Beta-Glucanase is an enzyme that breaks down glucan structures in fruits and grains.
• Phytase breaks organic-phosphate bonds, which helps destroy phytins and phytic acid, thereby ensuring that
important minerals are not complexed and transported unused out of the body.
• Alpha Amylase is an enzyme that helps digest starches and complex sugars present in plants.
• Glucoamylase aids digestion of polysaccharides and polymeric chains of glucose.
• Alpha-Galactosidase hydrolyzes bonds that hold galactose, thereby freeing the glactose
for its enzyme stimulating function involving DPP-IV.
One capsule with meals consisting of phenol containing foods. Start with ¼ to ½ capsule and gradually increase this dose to the amount that provides optimal digestion of foods.
The dose can be adjusted according to the specific needs of the individual. With small meals or snacks, smaller doses may be sufficient to provide adequate digestion of these foods. Avoid mixing with food or beverages that will be heated above 130° F as the activity of the enzymes will be adversely affected.
Enzymes should be taken at the beginning or early on in the meal to ensure appropriate digestion. The capsules may be swallowed whole or opened and mixed with food or beverages.
We recommend that Phenol Assist™ be used with Kirkman's Phenol Assist™ Companion (0262-090)
to help sulfation.
A list that details phenolic and salicylate content of foods follows:
Berries and cherries
Oranges and tangerines
HIGH TO MODERATE
Peaches and mangos
Broccoli and spinach
Lettuce and chinese vegetables (except iceberg/low)
Most nuts and seeds
LOW TO NEGLIGIBLE
Fats and oils