The use and effectiveness of magnesium supplementation is well documented. Magnesium is an essential mineral that is involved in many body functions as well as being a constituent of bones and teeth. It is essential for element of cellular metabolism and is an enzyme activator. Other body actions include:

Signs and symptoms of magnesium deficiency or inadequacy can include fatigue, mental confusion, heart disturbances, irritability, weakness, muscle spasms, loss of appetite, insomnia or a feeling of weakness. The Physician's Desk Reference for Nutritional Supplements states that some recent data of inpatient and outpatient populations, suggest that magnesium deficits may exist in from 12% to 40% of individuals.

Magnesium supplements usually have their beginning as minerals which have been influenced by our environment. For that reason, the purity of magnesium raw materials is important. Magnesium, like calcium, can have undesirable impurities present. The responsibility to assure the absence of lead and other heavy metals falls on the manufacturer. Kirkman uses only the purest forms of magnesium which have been tested for heavy metal content as well as other impurities.

There are many different forms of magnesium and the Physician's Desk Reference for Nutritional Supplements states that there is no compelling data indicating absorption differences. There are reported differences in how different forms affect the gastrointestinal tract, however. Below are some guidelines, though individual results may vary and should be discussed with your physician before administration.