Description
Melatonin is a hormone secreted in the human body by the pineal gland. It is manufactured
in that gland from serotonin. It is believed that manufacturing and secreting melatonin is the sole function of the pineal gland.
Melatonin
supplementation is used principally for:
Several double blind studies have shown that melatonin supplementation
is effective in promoting sleep when melatonin levels are low. If one takes melatonin when levels are not reduced, then it has reportedly
no effect. The reason for this is that the body normally secretes melatonin just before bedtime. Darkness stimulates melatonin secretion
while light suppresses it. This process is all controlled by an internal body clock governing hormonal secretions and is called
“natural circadian rhythm”. Low melatonin levels are considered a very common cause of sleeplessness.
In jet-lag, the natural body clock may not allow for secretion of
melatonin at the appropriate time, thereby making melatonin supplementation useful.
Poor methylators do not efficiently make melatonin from serotonin.
This can hinder P5P formation from vitamin B-6 which in turn leads to a nutritional shortfall of this important nutrient. For this
reason, we now recommend that everyone who uses Super Nu-Thera or Thera Response, also try melatonin in the evening to determine if
it provides added benefit in addition to sleep.
For those individuals who are deficient in glutathione, melatonin is
important because it stimulates the production of glutathione peroxidase.
Kirkman's
Melatonin Plus Magnesium is a melatonin supplement which
also contains 100 mg. of magnesium for additional benefits.
Magnesium can have a calming effect and may also relax nerve
impulses and muscle contractions.
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